The patent concerns a new formulation of buprenorphine, one of the medications shown to help people with opioid addiction. Exactly. By Roy Poses, MD, Clinical Associate Professor of Medicine at Brown University, and the President of FIRM – the Foundation for Integrity and Responsibility in Medicine. True health care reform requires all sorts of transparency, now particularly including transparency about corporate beneficial ownership. We get all hysterical because people get so messed up they die. But here’s the problem I see. Why the Sackler’s may have concealed their ownership of the company seems obvious. Each groupload of people should... Be careful what you wish for... Accountability has to start somewhere. if you have attention deficit hyperactivity disorder (adhd), your doctor may have prescribed adderall (the brand name for the drug amphetamine-dextroamphetamine) to help … Beneficial ownership simply refers to “anyone who enjoys the benefits of ownership of a security or property, without being on the record as being the owner.” (per Wikipedia). I wonder if the Sacklers have campaigned against legalized medical and recreational marijuana? Adderall XR, the long-acting version of Shire’s popular treatment Adderall, had for years been the company’s top-selling product, bringing in $1.1 billion in sales in 2008, about one-third of its revenue that year. (2011), prilocaine (citanest) Except we’re not even looking. But mindful that its blockbuster could soon face generic competition, Shire acted aggressively to protect its franchise. Created Date The Sackler’s generic drug company is now known to have paid physicians a small but important amount to assist in its marketing of opioids. Oxycodone ETH 462 So I think it is reasonable to say that whether Sackler-owned Rhodes Technologies/ Pharma was also used as a tool to conceal political influence remains a mystery. This brand-name drug is a combination of the generic drugs amphetamine and dextroamphetamine. In general, Adderall … It is unknown whether big pharmaceutical and other big health care corporations similarly have concealed beneficial ownership of other companies that could be used to conceal all manners of mischief. The case has some mysterious aspects. Adderall History: Shire Pharmaceuticals Group created the Adderall drug in 1996 and has continued to produce this drug until 2007. With commercial footprint in over 20 markets, Alvogen’s key regions include the U.S. and APAC regions. (2019), brompheniramine maleate (dimetane) Please login or register first to view this content. Rhodes Pharmaceuticals was set up in 2007, four months after Purdue pleaded guilty to federal criminal charges that it had mis-marketed OxyContin over the previous decade. (2020), fenofibrate (fenoglide) Per the FT. Purdue Pharma has always insisted that its drug OxyContin cannot be considered a prime culprit in the crisis because it accounts for only 1.7 per cent of overall opioid prescriptions in the US. News & Case Alert on Adderall XR. (1988), amphetamine (Adderall) Concealing who really owns a company enables concealing sources of funds (as in money laundering), market power (when the owner also owns competitors), and sources of political influence, and enables those benefiting from the actions of the company to escape responsibility for their consequences. After 2007, Teva Pharmaceuticals started to produce this drug. Anti-corruption campaigner have pushed to reveal the beneficial ownership of all corporate entities. They paid the most, $121K, to a single physician in Saint Charles, MO. (1982), Center for Research Innovation in Biotechnology Why is it likewise important for them to bribe physicians to push their opioids? Pill with imprint R P 30 is White, Round and has been identified as Oxycodone Hydrochloride 30 mg. However, just to be fair, drug companies take steps to reduce the addictive/abuse potential of these medications. (Phase 2), acetaminophen (tylenol) Adderall, Adderall XR, and Mydayis are combination drugs containing four salts of the two enantiomers of amphetamine, a central nervous system stimulant of the phenethylamine class. Shire is the original maker of Adderall until their patent expired. Adderall XR. This is so damn frustrating….. I’m 59 and have been on Adderall since the mid 90″s…. Alvogen is a global, privately owned pharmaceutical company focused on developing, manufacturing and selling generic, brand, over-the counter (OTC) and biosimilar products for patients around the world. Why is it important for the Sacklers to hide their beneficial ownership in pharmaceuticals? Opioids are dangerous. Let’s work back from that point: We need multiple levels of civilizing to address this problem if justice for addicts fails; as it has done. Quantity: 1 Pill The little-known company now makes several opioid-based products containing highly-addictive drugs such as oxycodone, morphine and hydrocodone, according to a US Food and Drug Administration database. We are proud to have a long history of developing and manufacturing pharmaceuticals in the United States. And etc. (2020), pseudoephedrine (Benylin) Round Yellow 4mg Tablets and 3-Sided White 8mg Tablets Manufacturers: Rhodes Pharmaceuticals. (Rhodes Pharmaceuticals) Extended-release capsule 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg: Capsule with multilayer beads; 40% of dose in the immediate-release layer and 60% in the extended-release layer (2nd peak at 7–8 hrs) 12 hours: Capsule may be opened and contents swallowed completely with applesauce: YES: Concerta® or generic The patent says that the faster the treatment dissolves, the less risk there is for diversion. We should resolve these issues like adults who recognize that opioids are dangerous but pleasant, and balance out our efforts to prevent death and destitution with not just standardized, reliable, cheap drugs, but with a certain amount of social acceptance and equity. FDA Listing of Authorized Generics as of December 28, 2020 Note: This list of authorized generic drugs (AGs) was created from a manual review of FDA’s database of annual reports submitted to the There's a lot of chemistry in that little pill that affects your nervous system. Adderall (amphetamine-dextroamphetamine mixed salts), Adderall XR are indicated for Attention Deficit Hyperactivity Disorder (ADHD), na rcolepsy, etc., in children more than 12 years old. Most of our products are made in-house at our facilities in the United States. 4240 Duncan Avenue, Suite 110 One of the Tea Party's biggest 'weapons' against... Ah yes! Pill with imprint RP 730 is Beige / Orange, Capsule-shape and has been identified as Amphetamine and Dextroamphetamine Extended Release 30 mg. Before sharing sensitive information, make sure you're on a federal government site. It reported. (2020), oxycodone (oxycontin) The Mystery of the Mysteriousness of the Rhodes Companies and Facility. A 2005 version of the Rhodes Technologies’ website GoLocal uncovered said, ‘We have very broad capabilities in developing sophisticated chemicals and offer confidential production of high purity APIs and finished dosage forms of innovative pharmaceuticals, as well as marketing and sales services. The FT report was noted by our local on-line news site, GoLocalProv, which tried to find out more about the company. By design, it helps generate social and legal immunity for the ways that money was accumulated. Admittedly, their contribution to physicians’ conflicts of interest was modest compared to that of the Sackler’s better known Purdue Pharma, $27.9M over the same time period, but it should not be overlooked. With the popularity of Narcos, when will Netflix create a bingeable mini-series on this family? Adderall is a central nervous system stimulant. So the good in opioids is that they are wonderfully relaxing and carefree. In September, the UK based Financial Times reported. GoLocalProv article included a blurry picture of a large factory building apparently copied from an old website. Also, they typically book numerous ski instructors through the Alf Engen Ski School, where I teach ‘This further debunks the Sackler family’s whole claim that they are not responsible for the crisis,’ said Andrew Kolodny, a professor at Brandeis University who is one of the foremost experts on the US addiction epidemic. Purdue Pharma had also worked with the Washington Legal Foundation to push against guidelines from the Centers for Disease Control that would have potentially reduced opioid prescribing. But the reasons for the company itself to maintain such a “low profile,” and for its facilities to be so well hidden, and to have such “massive security” (not otherwise described by GoLocalProv), are ongoing mysteries. One would think this would cut into their bottom line. Furthermore, we noted here that Rudolf Giuliani, now President Donald Trump’s lawyer, and previously and probably currently highly influential in the Trump regime, formerly represented Purdue Pharma and had helped mitigate the company’s punishment for past mischief, an interesting example of the revolving door from the pharmaceutical industry to government. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP … So we now know a bit more about the extent Sackler family owned opioid manufacturers enlisted physicians to market their products, at times deceptively. Adderall is used in the treatment of attention deficit hyperactivity disorder and narcolepsy. They have made little headway, so far. Rhodes is a diversified, dependable firm well positioned for partnerships.’, The marketing arm of the Rhodes Technologies is Rhodes Pharmaceuticals and it self-describes itself as ‘a privately held company headquartered in picturesque Rhode Island….developing and distributing quality pharmaceutical products since 2008.’. Action Date Submission Supplement Categories or Approval Type Letters, Reviews, Labels, Patient Package Insert Note Url; 07/03/2019: SUPPL-34: Labeling-Package Insert Attention Deficit Disorder with Hyperactivity So we now know that the Sackler Family, owner of Purdue Pharma, also owns a generic pharmaceutical company that manufacturers an important portion of the narcotics sold in the US. Originally published at Health Care Renewal, Mysteries still abound in the not so wonderful world of health care dysfunction, so, quick, the game’s afoot…. Let’s step back and start from an assumption that all things good can be resolved humanely. That’s where to start. (1998), naloxone (narcan) The Mystery of the Sackler Family’s Opioid Market Power Partly Solved. A search of the ProPublica “Dollars for Docs” data base revealed that Rhodes paid $1.43M to physicians from August, 2013, to December, 2016. Very interesting post – Arthur Sackler was also a silent partner in the creation of medical data marketing firm IMS Health (now IQVIA), which sells prescription information to drug companies so they can target doctors. Emails and requests for an interview were not responded to by Rhodes Pharmaceuticals. So in 1996, Shire Pharmaceuticals introduced Adderall, a patented blend of amphetamine salts, to compete in the market for ADD/ADHD medications. Rhodes Pharmaceuticals was set up in 2007, four months after Purdue pleaded guilty to federal criminal charges that it had mis-marketed OxyContin over the previous decade. It is also possible that the generic company also has been used to increase the family’s influence over politics and policy that increased opioid sales and hence its responsibility for the opioid epidemic. THat’s why the CIA hides the fact that they are big time drug dealers. A global leader in the Pharmaceutical Industries - developing, producing and marketing affordable, high quality generic drugs and specialty pharmaceuticals. Find Reviews, Ratings, Directions, Business Hours, Contact Information and book online appointment. PAINKILLERS; Adderall IR $ 210.00 – $ 450.00 Highlights Product Name: Adderall and Adderall XR Strength: 30mg Imprint: AD 30 Manufacturer: TEVA Inc.& Actavis Delivery Time: Discreet Overnight Delivery to USA & CANADA and 3 days Regular shipping worldwide Adderall is used to treat narcolepsy and attention deficit hyperactivity disorder For the Narcolepsy treatment, ADHD experts recommend Adderall to Adderall XR, which is an extension drug. Purdue Pharma certainly has a track record of such influence. However, I could find nothing, at least via web searching, to otherwise describe it. You can ask your doctor or pharmacist for information about Adderall that was written for healthcare professionals. (2020), buprenorphine The case of the mysteries surrounding Rhodes Technologies/ Pharma should be another impetus to support this campaign. Saint Louis, MO 63110, Rhodes Phamaceuticals, L.P. | RHODES PHARMS, Attention Deficit Disorder with Hyperactivity. However, Rhodes and Purdue combined accounted for 14.4m opioid prescriptions in 2016, according to figures seen by the FT, giving them a total share of 6 per cent of the US opioid market. I don’t. Today’s mysteries involve beneficial ownership. (2020), methylphenidate (ritalin) (1988), dexmethylphenidate (focalin) Despite its size, I could find no coverage of the company, the facility, the buidling of the facility (which likely was quite a project), or anything else relevant in local media, or on the web. No wonder the Sacklers have the means to take extended ski vacations at their private ski chalet in Alta Utah. Adam Tanner gives a detailed account in his book “Our Bodies, Our Data.”. adderall® 5 mg is a white to off-white tablet, which contains no color additives. Why the company and its physical plant were so secretive is not so clear. Elite Pharmaceuticals () has received FDA approval for a generic version of Shire's Adderall XR, an extended-release mixed salt of a single entity Amphetamine product with strengths of … He added: ‘They have always said, ‘Why is everyone picking on us, we’re only 2 per cent of prescriptions?’ A spokesperson for the family declined to comment. (2017), theophylline (synophylate) It is, in general, is tolerant and effective in treating symptoms of ADHD and narcolepsy. It is supplied by Rhodes Pharmaceuticals L.P. Imprint: R P 30 Strength: 30 mg Color: White Shape: Round An Odd Data Point From Cigna. The Sacklers are best known as the owners of Purdue Pharma, the privately held drugmaker that makes the now infamous opioid painkiller OxyContin, which has been described as ‘heroin in a pill’. (2017), codeine (Phenergan) Presently, two types of Adderall exist: Adderall XR (extended released) and Adderall IR (immediate release). This is admittedly speculation, but it is possible that Rhodes Technologies/ Pharma was also used as a vehicle for political influence to affect policy making relevant to the Sackler’s interests. This week Reactions takes a look at the science behind how Adderall works. The Mystery of the Sackler Family’s Political Influence. However, an FT analysis of company registration documents has established that the family also owns Rhodes Pharma, a little-known Rhode Island-based drugmaker that is among the largest producers of off-patent generic opioids in the US. So that’s a problem. Who the F cares if opioids are readily available if they are controlled and relatively benign? The medicine is also prescribed for the patients suffering from excessive uncontrollable daytime sleepiness, also known as narcolepsy. (Look here for the relevant report from Transparency International.) It is unknown whether the family owns similar companies that have not been discovered. The U.S. Patent and Trademakr [sic] Office information shows the Rhodes Technologies’ plant in Coventry, RI is assigned the patent for the new drug. (2017), dextroamphetamine (Dexedrine) (Phase 4), Keratoconjunctivitis Sicca (2015), morphine The .gov means it’s official. The case has recently been very well covered in the media. We need pharma to come up with very refined, reliable and standardized opioids – if that cuts into their profits then we should help them manage pure drugs that can be relied on; we should set prices for these drugs, whether over the counter or prescription, that are reasonable so that there is no insane profit motive for pharmaceutical companies, no black market – that’s where corruption begins. A second GoLocalProv article also revealed that, The billionaire family whose company is being sued by states and cities across the country for their role in creating the opioid crisis is now launching a new recently patented antidote for the drug known as ‘heroine in a pill.’. The billionaire Sackler family, which has been blamed for fuelling the US opioid addiction epidemic, owns a second drugmaker that churns out millions of addictive painkiller pills every year, the Financial Times can reveal. Note that the “new drug” that is considered an “antidote” to oxycodone is simply a minor modification of an old drug, buprenorphine, already used to treat opioid addiction. Labeler / Supplier: Mallinckrodt Pharmaceuticals National Drug Code (NDC): 00406-8530. no rx oxycodone overnight oxycodone R P 30. Calls and emails to Rhodes Technologies and its affiliated marketing company Rhodes Pharma have not been responded to. A few months ago, a big question about the beneficial ownership of a local (to me) company suggested important local and national health care implications, and yet the case has remained anechoic. Adderall XR (amphetamine-dextroamphetamine mixed salts extended-release), Aptensio XR* (methylphenidate extended- release), Adzenys XR-ODT (amphetamine)*, Concerta There’s considerable argument over whether the source of funds taints the beneficiary, which might do great things with it. Back to Top Resources Call your doctor for medical advice about side effects. Time for some of those vaunted universities and charitable foundations that benefited from the Sacklers attempts to whitewash their reputation to return the money. (Phase 4), Dry Eye Syndromes Rhodes Pharmaceuticals, L.P. Report issue. Thus, it is likely that the Sackler family’s responsibility for the ongoing opioid epidemic is larger than was previously appreciated. Per Stat News. (1992), lidocaine (xylocaine) Who say that crime doesn’t pay? (almost) to die for. It appears that the Sackler’s concealed ownership of Rhodes Technologies/ Pharma also put them in a position to generate more financial conflicts of interest among physicians which could be used to enable more deceptive marketing. (Phase 2), Hyperkinesis For profit Phase 2 Phase 3 Phase 4. Thus the share of the opioid market held by the Sackler family is likely four times larger than was previously apparent . Adderall and Mydayis are trade names for a combination drug containing four salts of amphetamine.The mixture is composed of equal parts racemic amphetamine and dextroamphetamine, which produces a (3:1) ratio between dextroamphetamine and levoamphetamine, the two enantiomers of amphetamine.