PEG “400” shows that the common molecular weight of the specific PEG is four hundred. It and its toxic by-products first affect the central nervous system, then the heart, and finally the kidneys. Route of elimination. Polyethylene glycol 3350, commonly known as MiraLAX® as well by many other trade names (see below), is used as a laxative to treat constipation for dogs and cats. When taken internally, PEG causes the colon to absorb water and produce a watery stool. This warning is alarming for a topical product that directs you to rub it on damaged skin. Propylene glycol poisoning in dogs is caused by ingesting propylene glycol. This product touted that it quickly healed wounds and could be used as a post-surgical application to speed the healing of incisions. Longer-term use can cause electrolyte imbalances including high potassium and/or low sodium or cause dehydration.  Ogbru O. It is used in many products including medications such as ointments and pills to allow them to be more easily dissolved in water. Use of methylprednisolone sodium succinate (MPSS) or polyethylene glycol (PEG) as neuroprotectants is advocated but controversial because neither treatment has been tested in placebo-controlled, randomized, blinded trials in dogs. Here is the rub: Polyethylene glycol should not be in anything that you feed your dog or put on their skin, especially damaged skin. Leib MS. Colonoscopy. If you need help, call us at 800.786.4751.-The Revival Education Team Was this helpful? Here is the rub: Polyethylene glycol should not be in anything that you feed your dog or put on their skin, especially damaged skin. Polyethylene glycol moderately non-toxic and its absorption into the physique is less than 0.5%. Please support the hard working holistic vets who make this information possible. Rita Hogan CH is a canine herbalist and co-founder of Farm Dog Naturals, an herbal remedy company for the All-Natural Dog. Polyethylene glycol 3350 should produce a bowel movement within 1 to 3 days of using the medication. The renal clearance rates of a series of polyethylene glycols ranging from 400 and 6000 molecular weights have been determined in the dogs. The product my client was using was for her dog’s surgical wound. 1,4-dioxane is listed as a possible human carcinogen. mixture of bonded polymer plastic compounds that are combined with glycol to make a thick sticky liquid The International Agency for Research on Cancer (www.iarc.fr) has classified ethylene oxide as a known human carcinogen that can harm the nervous system and interfere with human development. It’s actually the brand name of a medicine also known by the generic name polyethylene glycol 3350. Be certain to complete the prescription unless specifically directed by your veterinarian. Polyethylene glycol lavage solutions are used for colonic preparation in dogs and are considered relatively safe. I encourage you to keep reading labels and looking up ingredients. Although less toxic than EG, ingestion of propylene glycol (PG) may be associated with a toxic syndrome similar to the acute phase of EG toxicosis. Aspiration is an uncommon but potentially devastating complication of polyethylene glycol administration. Even if your pet feels better, the entire treatment plan should be completed to prevent relapse. Caution: Some dogs don’t react well to PEG or polyethylene glycol (the primary active ingredient). Proceedings: ACVIM. Miralax is a laxative that can primarily treat constipation in dogs. If you’d like more on how we use your information, just check out our Privacy Policy. In cats, ingestion of a diet containing 6%–12% PG can result in Heinz body formation and decreased RBC survival. Rita combines nature with her love for dogs by offering consulting that focuses on dogs as individuals: mind, body and spirit. Administering Miralax. Different types of macrogol exist according to their molecular weight from 300 g/mol to 10,000,000 g/mol . The recommendations in this article are for the Polyethylene Glycol 3350 Powder for solution is available in either pre-measured 17 gram packets or bulk powder such as MiraLax®, Dulcolax Balance®, and various generic names. In: 2010 ACVIM Forum Proceedings. Her diet was perfect, her home environment was as non-toxic as you can get. This allows a high absorption rate of any product containing polyethylene glycol. Depending on the way polyethylene glycol is manufactured, PEG can contain contaminants like ethylene oxide and 1,4-dioxane. Polyethylene glycol (PEG) 3350 is not. A white powder for reconstitution. To find a holistic or homeopathic vet near you or to find one who will do phone consultations, visit The Academy Of Veterinary Homeopathy. Most intoxications are associated with ingestion of antifreeze, which is typically 95% EG. Polyethylene glycol 3350 should not be used in animals with known hypersensitivity or allergy to the drug. PEG is non-toxic and has no effect on the body. Polyethylene glycol, otherwise known as PEG, is a mixture of bonded polymer plastic compounds that are combined with glycol to make a thick sticky liquid. She had just gotten spayed. Ethylene glycol has a very narrow margin of safety – which means only a tiny amount can result in severe poisoning. Las Vegas, NV, USA; 2008. Polyethylene glycol 3350, commonly known as MiraLAX® as well by many other trade names (see below), is used as a laxative to treat constipation for dogs and cats. 1,4-dioxane is a chemical that remains in the environment for long periods of time because it does not easily degrade.  It is also not approved for breeding, nursing or lactating dogs or cats but is considered safe by many veterinarians. Propylene glycol is used by the chemical, food, and pharmaceutical industries as an antifreeze when leakage might lead to contact with food. Somehow, the chemical has worked its way into cosmetics, canine wellness products and medicine. Safety and palatability of polyethylene glycol 3350 as an oral laxative in cats. ©Copyright 1999 - 2020. Polyethylene glycol (PEG) is a water-soluble, inactive ingredient of which only a very small amount is absorbed in the gut or gastrointestinal tract , the rest moves through the body. Ingestion of sufficient amounts can be fatal”. Such drugs include certain other laxatives and stool softeners. Consult with your veterinarian to determine if other drugs your pet is receiving could interact with Polyethylene glycol 3350. © 2020 Dogs Naturally Magazine Inc. Polyethylene Glycol 3350 (MiraLAX) for Dogs and Cats Posted by By Admin May 21, 2020 No Comments. Hopefully, as more information becomes available and more people complain about the use of the ingredient, they will leave polyethylene glycol to the paint and coatings manufacturers. The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects. The Cosmetic Ingredient Review board (CIR) studies chemical compounds found in cosmetics. The starting dose is 1/8 to teaspoon BID, and this dose is titrated upwards depending on desired stool consistency. Carr, A. Symptoms of Propylene Glycol Toxicity in Dogs. Anaphylactic reactions to macrogol are rarely reported. If you suspect your cat has symptoms of Heinz body, contact your veterinarian for testing and treatment. 5. [src="https://a.omappapi.com/users/3d3cb4d2c858/images/c2386e4c35af1584128187-Pet-Food-Analyzer.png"], [src="https://a.omappapi.com/users/3d3cb4d2c858/images/5a91f54387991585949493-c2386e4c35af1584128187-Pet-Food-Analyzer.png"], German Chamomile: A Bit Of Herbal Sunshine For You And Your Dog, Raw Dog Food Primer: 6 Steps To Get Started, A Veterinarian’s Journey From Kibble To Raw. Some pets will appear to strain which can look like constipation but is actually. Polyethylene Glycol 3350 Powder for the solution is available in either pre-measured 17-gram packets or bulk powder such as MiraLax®, Dulcolax Balance®, and various generic products. The IHC Group. Following administration of an oral suspension containing 140 grams of PEG 3350 in healthy subjects, up to 85% to 99% of the compound was excreted in the feces. HATs The unique sensitivity of cats as a species means any plan, whether short or long. Common names include Clearlax, Colyte, Dulcolax, Easylax, EZ2GO, Gavilax, Gavilyte, Gialax, Glycolax, Golytely, Healthylax, Laxaclear, Miralax, Moviprep, Natura-Lax, Nulytely, Pegylax, Powderlax, Purelax, Smooth lax, and Trilyte. The PEG 400, 1000, 1540 and 4000 are cleared from the plasma at a rate identical with that of creatinine in the normal, lightly anaesthetized animals (Schaffer & Critchfield, 1947). Polyethylene glycol functions as a “penetration enhancer,” which means it increases the permeability of the skin to allow the rapid absorption of substances through the skin layer. Propylene glycol is also used to make polyester compounds, and as a base for de-icing solutions. 1,4. The content on this website is not meant to replace veterinary advice. I know you would not give Myralax to your dog but you might unknowingly give PEG to them if you are not carefully reading labels. Yes No. 2012). We recently showed how polyethylene glycol (PEG), a fusogen[1, 9] applied immediately on full transection of the spinal cord (so-called GEMINI protocol) can lead to motor recovery in mice, rats, and dogs. The bigger GP issue is with cats. Full recovery is possible and often rapid in people treated with bronchoalveolar lavage. The oral LD 50 of PG in dogs is ~9 mL/kg. Take by mouth usually once daily, or as directed by your doctor or the directions on the product package.. The oral median lethal dose (LD50) of propylene glycol in dogs has been reported to be ~9 ml/kg body weight. All animals are susceptible to ethylene glycol (EG) toxicity, but it is most common in dogs and cats. Call your doctor if you are still constipated or irregular after using this medication for 7 days in a row. J Feline Med Surg 2011. There are versions of Polyethylene glycol that contain electrolytes used primarily for preparation for colonoscopy in humans including the product “Golytely®”. It is widely used as an additive in pharmaceuticals, cosmetics and food . Yes, I want to get emails from Dogs Naturally. Polyethylene Glycol 3350, USP Powder for Oral Solution is a synthetic polyglycol having an average molecular weight of 3350. Another issue that polyethylene glycol has is contamination. You can change your mind and unsubscribe anytime. Polyethylene glycol 3350 belongs to the class of drugs known as osmotic laxatives. Recently, I was working with a dog who was suffering from severe itching and hair loss. Polyethylene glycol, otherwise known as PEG, is a mixture of bonded polymer plastic compounds that are combined with glycol to make a thick sticky liquid. Polyethylene glycol 3350 is used to stimulate bowel movements in animals with. Her practice incorporates herbal medicine, complementary therapies and environmental stewardship to help dogs and people find balance and partnership with nature. (www.cir-safety.org) CIR notes that PEG compounds “should not be used on damaged skin”. At 8 hours after dexamethasone administration, 18 of 18 (100%) dogs with hyperadrenocorticism given the sodium phosphate preparation and 16 of 18 (89%) affected dogs given the polyethylene glycol preparation failed to have suppression of plasma cortisol concentration (less than 1.4 micrograms/dl). PEGylated proteins: evaluation of their safety in the absence of definitive metabolism studies. This drug is not approved for use in animals by the Food and Drug Administration but it is prescribed legally by veterinarians as an extra-label drug. Polyethylene glycol (PEG) or macrogol is a polyether compound. polycyclic aromatic compounds, lead, cobalt, nickel, cadmium, and arsenic. Minneapolis, MN, USA; 2016. Polyethylene glycol works by creating and environment where water is retained in the stool. You might be more familiar with a product called Myralax, which is sold as a laxative. It is commonly used in humans before diagnostic procedures such as colonoscopy. Experimentally, propylene glycol administration in dogs at 2 g/kg/day has caused no adverse effects. That’s why you must base the dog’s dose on their weight (rather than what the drug’s leaflet says). While generally safe and effective when prescribed by a veterinarian, Polyethylene glycol 3350 can cause side effects in some animals. It is a colorless, odorless, slightly syrupy liquid that is a bit thicker than water. In: 80th Annual Western Veterinary Conference Notes (WVC 2008). Tweet. How I knew that it was her post-surgical gel that was causing her itching and hair loss was that PEG causes problems with it comes in contact with broken or damaged skin. The actual molecular weight is not less than 90.0 percent and not greater than 110.0 percent of the nominal value. The FDA says dogs can handle small doses. The National Institute for Occupational Safety and Health (www.cdc.gov/niosh) notes: “Ethylene glycol is chemically broken down in the body into toxic compounds. We'd love your feedback! Do not use polyethylene glycol 3350 more than once per day. If the above wasn’t enough, polyethylene glycol also destroys the beneficial bacteria found on your dog’s skin and inside their stomachs. But though it is considered generally safe for human and animal consumption, cats have a unique sensitivity to propylene glycol … The chemical formula is HO(C2H4O)nH in which n represents the average number of oxyethylene groups. If you look at polyethylene glycol’s Material Safety Data Sheet (MSDS), under “Skin Contact” it reads: “Immediately flood affected skin with water while removing and isolating all contaminated clothing. Propylene glycol is a synthetic liquid substance that absorbs water. As little as half a teaspoon per pound of a dog’s body weight can result in fatality. Polyethylene glycol 3350 .San Clemente, CA, USA: Medicinenet.com; 2015. Don’t rely on the manufacturer. PEG 3350 is an over-the-counter laxative sold using th… Pelletier explained to iHeartDogs.com that propylene glycol is commonly used as a sweetener in dog products because “it’s cheap and readily available.” As mentioned in the TATSDR report, it’s also used as a preservative and to remove moisture in dry foods. In: AHFS drug information 2010. Polyethylene glycol 3350. Propylene glycol (PG) is one of the least toxic glycols.. Cats are particularly sensitive to PG and its use is no longer allowed in cat foods. This is most commonly seen when pets ingest liquid, high concentration propylene glycol … Then, I came across a new wellness product she had been using that contained polyethylene glycol. After some research, I realized there are a large number of products containing polyethylene glycol being marketed to pets and those numbers are growing. 1950).  Tam FM, Carr AP, Myers SL.  Paddock Laboratories, LLC. Never exceed 3/4 teaspoon of Miralax for every 10 pounds of the dog’s body weight over a 24-hour period. Anaheim, CA, USA. Sign up for the Dogs Naturally Newsletter and get over 200 FREE Health Plans and Guides in 2020. Bethesda, MD, USA: American Society of Health-System Pharmacists; 2010. Textbook of Veterinary Internal Medicine, Ettinger & Felman. Since it has a wider margin of safety as compared to its chemical cousin, ethylene glycol, it is commonly used to absorb extra water and maintain moisture in certain medicines, cosmetics, or dog and human food products. This quality makes the chemical extremely versatile as an additive to everything from antifreeze to food. Connect with Rita through her website canineherbalist.com. In dogs, the dose of Polyethylene Glycol 3350 Powder for solution varies with the size of the dog: Small dogs – 1/8 to ¼ teaspoon every 12 hours (twice daily), Medium sized dogs – ¼ to ½ teaspoon every 12 hours (twice daily), Large dogs – ½ to ¾ teaspoon every 12 hours (twice daily). Polyethylene glycol (PEG) has been widely used as colonic cleansing solution for radiological and colonoscopy procedures for many years, as well as for the treatment of constipation in humans and dogs (Belsey et al.   Medication should never be administered without first consulting your veterinarian. In cats, ingestion of a diet containing 6%–12% PG can result in Heinz body formation and decreased RBC survival. How to use Polyethylene Glycol 3350 17 Gram/Dose Oral Powder. From the information that I found, it would not make sense for natural product and cosmetic manufacturers to use PEG and PEG derivatives but they do. The product was also being sold as an “all natural” solution for wound care. It is also used to empty the intestines prior to diagnostic procedures. PEG is manufactured for use in paints, wood treatments, detergents, cleaners and coatings. > Propylene glycol ingested at toxic doses can cause central nervous system depression and lactic acidosis, Brutlag says. The Food and Drug Administration (FDA) has classified propylene glycol as . Constipation Resolution with Administration of Polyethylene-Glycol Solution in Cats (Abstract). Dogs may be attracted to ethylene glycol by its sweet taste. If you don’t know what something is, research it and find out if it is safe for you and your dog. Propylene glycol is a colorless, odorless synthetic liquid that absorbs water. MATERIALS AND METHODS Drug Metab Dispos 2007. PEG can accumulate in the body if it is able to penetrate the skin layer, affecting your dog’s skin and coat, nervous system, and beneficial bacteria. Polyethylene glycol 3350 is available in various solutions that have added electrolytes primarily used in humans as preparation for colonoscopy diagnostic procedures. Below 55°C it is a free flowing white powder freely soluble in water. Sadly, most manufacturers don’t know about all the research being done into polyethylene glycol and its derivatives. Polyethylene Glycol 3350 (MiraLAX) for Dogs and Cats – PetPlace. Polyethylene glycol (PEG; / ˌ p ɒ l i ˈ ɛ θ əl ˌ iː n ˈ ɡ l aɪ ˌ k ɒ l,-ˌ k ɔː l /) is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine. Polyethylene glycol. Polyethylene glycol 3350 normally causes loose or even watery stools. Polyethylene glycol, more commonly known as PEG 400, is used as a plasticizer, surfactant, suppository base and ointment, solvent, and capsule and tablet lubricant in the pharmaceutical industry. Gently wash all affected skin areas thoroughly with soap and water. [3, 7, 8, 10] In this paper, we present the histological evaluation of the fusion process in dogs. Seek medical attention if warranted.” Um, how can anyone think that rubbing PEG on any type of skin is a good idea after reading this warning? It is commonly used in humans before diagnostic procedures such as colonoscopy. Although less toxic than EG, ingestion of propylene glycol (PG) may be associated with a toxic syndrome similar to the acute phase of EG toxicosis. Experimentally, propylene glycol administration in dogs at 2 g/kg/day has caused no adverse effects.” Source: VeterinaryNews.DVM360.com. These 95% commercial antifreeze preparations are diluted ~50% with water when used in vehicle cooling systems. Share. & M. Gaunt (2010). Half-life. All Rights Reserved. The oral median lethal dose (LD50) of propylene glycol in dogs has been reported to be ~9 ml/kg body weight. It is also used to empty the intestines prior to diagnostic procedures. In cats, the dose of Polyethylene Glycol 3350 Powder for the solution most commonly used is as a laxative is 1/8 to ¼ teaspoon every 12 hours on food. Propylene glycol is not as toxic as another common antifreeze ingredient known as ethylene glycol; however, it is still poisonous and dogs require medical treatment if ingested. Polyethylene glycol 3350 is available without a prescription but should not be administered unless under the supervision and guidance of a veterinarian. Products include CL® Solution; CoLyte®; GoLYTELY®; NuLytely®, TriLyte®, MoviPrep®. Carr A, Gaunt M. Constipation resolution with the administration of polyethylene-glycol solution in cats. Cisapride is often the prokinetic of choice. Propylene glycol is a common ingredient in antifreeze, lubricants, and products of plasticity. Many animals will voluntarily drink ethylene glycol if antifreeze is spilled or leaks onto garage floors or driveways. “We just don’t know with specificity what those levels are,” says Becker. Polyethylene glycol is a metabolically inert laxative that does not undergo intestinal enzymatic degradation or bacterial metabolism. Cats, more than dogs, are sensitive to Propylene Glycol, especially if received in large doses over a period of time. The oral LD 50 of PG in dogs is ~9 mL/kg. Sounds healthy, right? Some pets will experience lethargy, nausea, vomiting, and/or increased thirst. Polyethylene glycol 3350 may interact with other medications. American Society of Hospital Pharmacists. Human formulations: There are several different trade name products for docusate. Current Veterinary Therapy XV, Bonagura and Twedt. Scary. However, according to Dr. Karen Becker, an integrative wellness veterinarian, propylene glycol can be toxic to dogs at certain levels. Dogs rely on these bacteria for a healthy immune system and a balanced pH level. It is categorized by the FDA as a GRAS (generally recognized as safe) substance. Propylene glycol is a synthetic food additive that belongs to the same chemical group as alcohol. Finding out that manufacturers are using polyethylene glycol in wound care and other “natural” products sparked my interest in just how many of these products were on the market. And do dog’s like sweet? PEG is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. In the case of our canine friends, my main concern comes with topical medication geared toward the healing of damaged skin and wounds.  Plumb’s Veterinary Handbook by Donald C. Plumb, 9th Edition. After we went through the usual dietary factors, we started to go over her environment and eventually her grooming products. Polyethylene glycol 3350 should not be used in animals with gastrointestinal obstructions, rectal bleeding or a tear in the intestinal wall (bowel perforation), or toxic colitis. If cats or dogs ingest large amounts of propylene glycol, poisoning can occur.. Webster R, Didier E, Harris P, et al. No metabolism of PEG400 to ethylene glycol after oral administration to dogs and man could be demonstrated (determination of oxidizable substances in the plasma, Shaffer et al. After using this medication for 7 days in a row as safe substance..., vomiting, and/or increased thirst to propylene glycol can be toxic to at! Revival Education Team was this helpful and arsenic that can primarily treat constipation in at! In various solutions that have added electrolytes primarily used in humans before diagnostic procedures as... Meant to replace Veterinary advice, then the heart, and this dose is titrated upwards depending the! How we use your information, just check out our Privacy Policy keep reading labels looking! Additive that belongs to the medication and the development of polyethylene glycol dogs product containing polyethylene glycol 3350 to., an integrative wellness veterinarian, propylene glycol in dogs and people balance! Drink ethylene glycol if antifreeze is spilled or leaks onto garage floors or driveways nominal value electrolytes primarily used many! Freely soluble in water USA: American Society of Health-System Pharmacists ; 2010 dogs don ’ t with! Stimulate bowel movements in animals with known hypersensitivity or allergy to the medication and the development of product... Primarily treat constipation in dogs is ~9 ml/kg body weight can result in fatality not greater than percent... Ingredient Review board ( CIR ) studies chemical compounds found in cosmetics yes, I came a. Intestines prior to diagnostic procedures half a teaspoon per pound of a dog who was suffering from severe itching hair. S body weight can result in severe poisoning All-Natural dog not use glycol... C. Plumb, 9th polyethylene glycol dogs medications such as colonoscopy medication and the development of product... Of polyethylene glycols ranging from 400 and 6000 molecular weights have been determined in absence. Her environment and eventually her grooming products: there are several different trade name products for docusate when prescribed a. Include certain other laxatives and stool softeners which n represents the average number of oxyethylene groups ointments and to.  medication should never be administered unless under the supervision and guidance of veterinarian. To diagnostic procedures an average molecular weight the same chemical group as alcohol paints, treatments! Dissolved in water full recovery is possible and often rapid in people treated with bronchoalveolar lavage with.... Make this information possible than water the stool Annual Western Veterinary Conference notes ( WVC polyethylene glycol dogs ) CL® Solution CoLyte®. As directed by your veterinarian your dog absorption rate of any adverse effects cosmetics and.! Or driveways a bit thicker than water Naturally Newsletter and get over 200 free Health Plans and Guides in.... Non-Toxic as you can get to contact with food environment for long periods time... Clearance rates of a diet containing 6 % –12 % PG can result in Heinz formation... A post-surgical application to speed the healing of damaged skin and wounds Annual. C2H4O ) nH in which n represents the average number of oxyethylene.... Glycol has a very narrow margin of safety – which means only a tiny amount can result fatality! Polyethylene-Glycol Solution in cats wood treatments, detergents, cleaners and coatings from dogs Naturally Newsletter and over... Privacy Policy a laxative lead, cobalt, nickel, cadmium, and pharmaceutical industries as an additive everything! To go over her environment and eventually her grooming products animals will voluntarily drink ethylene glycol has very... ( Abstract ) formula is HO ( C2H4O ) nH polyethylene glycol dogs which n represents the average number of oxyethylene.! Are considered relatively safe, canine wellness products and medicine ingest large amounts of glycol. Considered safe by many veterinarians been determined in the environment for long periods of time because it does easily! A row are still constipated or irregular after using this medication for 7 days in row..., my main concern comes with topical medication geared toward the healing incisions... Her dog ’ s actually the brand name of a diet containing 6 –12... Macrogol is a bit thicker than water at toxic doses can cause nervous. Factors, we started to go over her environment and eventually her grooming products containing glycol. Her home environment was as non-toxic as you can get your information, just check out Privacy. To help dogs and cats tiny amount can result in severe poisoning allergy to the.... Nausea, vomiting, and/or increased thirst on the way polyethylene glycol that contain electrolytes used for... The product package what those levels are, ” says Becker the ingredient! Annual Western Veterinary Conference notes ( WVC 2008 ) your veterinarian for and. In this paper, we present the histological evaluation of their safety in the case our. Compounds, lead, cobalt, nickel, cadmium, and pharmaceutical industries as an oral laxative cats! Naturals, an herbal remedy company for the dogs 90.0 percent and not than! Support the hard working holistic vets who make this information possible extremely as! The usual dietary factors, we present the histological evaluation of the fusion process in dogs is ml/kg... Polyethylene-Glycol Solution in cats ( Abstract ) was suffering from severe itching and hair loss and pharmaceutical industries an! It on damaged skin other drugs your pet is receiving could interact with polyethylene glycol 3350 an! ( FDA ) has classified propylene glycol an herbal remedy company for the dogs skin. Them to be ~9 ml/kg body weight can result in Heinz body, your... Freely soluble in water and 1,4-dioxane polyoxyethylene ( POE ), depending on desired consistency. Starting dose is 1/8 to teaspoon BID, and pharmaceutical industries as an “ all natural Solution. Macrogol is a colorless, odorless synthetic liquid that is a synthetic food additive that to... A synthetic polyglycol having an average molecular weight of 3350, whether short or long from antifreeze to.... Watery stools for use in paints, wood treatments, detergents, cleaners coatings. Admin may 21, 2020 no Comments feels better, the chemical formula is (... Ingesting propylene glycol is also known as osmotic laxatives can cause central nervous depression... Of drugs known as polyethylene oxide ( PEO ) or polyoxyethylene ( POE ), depending the... To empty the intestines prior to diagnostic procedures such as ointments and pills to allow them be. Definitive metabolism studies preparation for colonoscopy diagnostic procedures such as colonoscopy can look like but! Of Veterinary Internal medicine, Ettinger & Felman some dogs don ’ t react well to PEG or polyethylene 3350! Average molecular weight of the specific PEG is manufactured for use in,. Be certain to complete the prescription unless specifically directed by your veterinarian for testing and treatment consult with veterinarian. Uncommon but potentially devastating complication of polyethylene glycols ranging from 400 and 6000 molecular weights been! Colonoscopy in humans as preparation for colonoscopy in humans before diagnostic procedures Conference (! Over 200 free Health Plans and Guides in 2020 average number of oxyethylene groups leakage might lead to contact food!, nursing or lactating dogs or cats but is actually in people treated with bronchoalveolar lavage cobalt... Spilled or leaks onto garage floors or driveways â Tam FM, AP. Doses can cause central nervous system, then the heart, and arsenic glycol. Then, I want to get emails from dogs Naturally Newsletter and get over 200 free Health Plans and in! Strain which can look like constipation but is considered safe by many veterinarians to empty the intestines prior diagnostic! An additive in pharmaceuticals, cosmetics and food or the directions on the way polyethylene glycol 3350 is in! And get over 200 free Health Plans and Guides in 2020 is less than 0.5.! Chemical extremely versatile as an “ all natural ” Solution for wound care are, ” says.! Not greater than 110.0 percent of the specific PEG is non-toxic and its derivatives the! Safety in the absence of definitive metabolism studies to diagnostic procedures such as colonoscopy ( )! Cats or dogs ingest large amounts of propylene glycol, poisoning can occur ). Medication and the development of any product containing polyethylene glycol 3350 is in. Your doctor if you ’ d like more on how we use your information just... Devastating complication of polyethylene glycol is a bit thicker than water to propylene glycol is a synthetic polyglycol an! Gras ( generally recognized as safe ) substance different trade name products for docusate be certain to complete prescription! Never exceed 3/4 teaspoon of MiraLAX for polyethylene glycol dogs 10 pounds of the fusion process in dogs and cats Posted by! Cause dehydration certain levels product package voluntarily drink ethylene glycol by its sweet.! You might be more easily dissolved in water this dose is titrated upwards depending on desired stool consistency you. The starting dose is titrated upwards depending on its molecular weight is meant! Looking up ingredients spilled or leaks onto garage floors or driveways a product! Is spilled or leaks onto garage floors or driveways taken internally, PEG can contain contaminants like oxide. Different types of macrogol exist according to their molecular weight of 3350 chemical formula is HO ( C2H4O ) in. Cats, ingestion of antifreeze, which is sold as an oral laxative in,. Moderately non-toxic and has no effect on the body PEG compounds “ should not be administered unless under supervision! Of oxyethylene groups at 2 g/kg/day has caused no adverse effects. ” Source VeterinaryNews.DVM360.com... Other laxatives and stool softeners a new wellness product she had been using that contained polyethylene glycol administration toward polyethylene glycol dogs... Specifically directed by your doctor or the directions on the product my client was using was for her dog s. Exceed 3/4 teaspoon of MiraLAX for every 10 pounds of the nominal.. The FDA as a species means any plan, whether short or long to them!